The proper article for is "El" (as in El Patrón del Mal ), but if you are referring to the full title in a sentence, in Spanish you would generally use "El" before the entire title only if the grammatical context requires it (e.g., El 'Pablo Escobar: El Patrón del Mal' es una serie ). In English, no article is needed before the title unless the sentence structure demands it (e.g., In 'Pablo Escobar: El Patrón del Mal'... ).
If your question is about the itself, it is "El" (masculine singular), as in El Patrón del Mal ("The Lord of Evil"). pablo escobar: el patrón del mal